Trusted Resources: Education
Scientific literature and patient education texts
Amyloidosis: A Unifying Diagnosis for Nephrotic Syndrome and Congestive Cardiac Failure
source: BMJ Case Reports
year: 2018
authors: Sara JDS, Khodadadi R, Barth D, Burton MC
summary/abstract:Diagnosing patients simply with heart failure or nephrotic syndrome is insufficient, and clinicians should always search for the underlying causes of these syndromes. Amyloidosis represents a rare group of diseases in which abnormal protein, namely amyloid fibrils, build up in various organs. Presentation depends on which organ systems are involved, and symptoms could include breathlessness associated with fluid overload suggestive of cardiac and/or renal involvement and diarrhoea and weight loss, suggestive of gastrointestinal involvement. The authors present a case of congestive cardiac failure and nephrotic range proteinuria in a patient with persistent fluid overload secondary toamyloid light-chain (AL) amyloidosis.
organization: Mayo Clinic, USADOI: 10.1136/bcr-2018-224317
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