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UPCOMING SESSIONS in ET
Tue, Jul 21, 2026 · 5:00 – 6:00 AM Bangkok
Taking Control of Your Health Care: Navigating and Maximizing the Patient Portal
Tricia Walker
Click Here To Register
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BofA Turns More Cautious On Alnylam’s ATTR-CM Story

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What's going on here?

BofA Securities just got more cautious on Alnylam’s heart-drug story, trimming its peak sales view to $11.8 billion and cutting its price target to $410.

What does this mean?

BofA, a major US bank, thinks Alnylam’s next quarterly update could do more than set a short-term tone: it may help investors pin down where 2026 revenue lands inside management’s guidance, and whether that range tightens again. The firm still sees a big market for transthyretin amyloid cardiomyopathy (ATTR-CM), a condition where a misfolded protein builds up in the heart, but it wants more proof on how competition and insurers will shape long-run demand.