Heart-Liver-Kidney Transplantation for AL Amyloidosis Using Normothermic Recovery and Storage From a Donor Following Circulatory Death: Short-Term Outcome in a First-in-World Experience

This article reports a landmark first-in-world case of triple organ transplantation for advanced AL amyloidosis, using a heart, liver, and kidney recovered from a donation-after-circulatory-death donor through thoracoabdominal normothermic regional perfusion. Published as a case report in the American Journal of Transplantation, the paper focuses on a 40-year-old man with severe multiorgan AL amyloidosis whose disease had progressed to the point that, without urgent transplantation, his prognosis was terminal. The report is important because it combines two major advances in one procedure: a heart-liver-kidney transplant for AL amyloidosis and the use of normothermic donor recovery and storage techniques from a DCD donor.