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An easily accessible diagnostic test called pain-related evoked potentials with concentric electrodes (PrEP-CE) may help detect the onset of hereditary transthyretin amyloidosis with polyneuropathy (hATTR-PN), according to a small study in Brazil.
Changes in PrEP-CE measures were able to discriminate between people with manifest hATTR-PN and those carrying disease-causing mutations but not yet showing symptoms, data showed.