UPCOMING SESSIONS in ET
Wed, Apr 15, 2026
3:00 – 5:00 PM UTC
Newly Diagnosed ATTR Patients Onboarding Session Dr. Stacey Goodman Click To Register
UPCOMING SESSIONS in ET
Wed, Apr 15, 2026 · 3:00 – 5:00 PM UTC
Newly Diagnosed ATTR Patients Onboarding Session
Dr. Stacey Goodman
Click To Register
View all sessions

Endomyocardial Biopsy Revisited: Diagnostic Value and Expanding Roles in Cardiac Amyloidosis

Source
Springer Nature Link

Abstract

Purpose of Review

Cardiac amyloidosis (CA) results from myocardial infiltration by misfolded amyloidogenic proteins and represents a heterogeneous group of diseases with distinct prognostic and therapeutic implications. While transthyretin amyloidosis (ATTR) and immunoglobulin light-chain amyloidosis (AL) account for the majority of clinically relevant cases, several rarer amyloid subtypes with cardiac involvement have been described.This review focusses on the role of EMB in CA, highlights its diagnostic andprognostic value, discusses procedural considerations, and outlines emergingperspectives, including its potential role in phenotyping amyloid clearance andassessing treatment response in the era of novel disease-modifying therapies.