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summary/abstract
If you have a type of amyloidosis called transthyretin amyloid cardiomyopathy (ATTR-CM), edema (swelling) is one of the most common symptoms. Edema happens when fluid gets trapped in body tissues, causing them to swell and look puffy.
Edema can be uncomfortable, affect movement, and make areas like your legs and feet sore or painful. Lifestyle changes and certain treatments may help reduce swelling and make it easier to manage.