Rare case of young cardiac amyloidosis: difficult diagnostic pathway in routine clinical care

Abstract

Background

Light-chain amyloidosis (AL) is a rare plasma cell disorder characterized by extracellular deposition of misfolded light chains in multiple organs, typically manifesting with non-specific symptoms that result in delayed diagnosis. Cardiac involvement is a major adverse prognostic factor. The incidence peaks around the age of 65, and occurrence in younger individuals is exceptionally rare, further complicating timely recognition.