Key Information
ATTR-cardiac amyloidosis (ATTR-CM) is a serious but often overlooked heart condition that disproportionately affects Black communitiesexternal link, opens in a new tab. This was the focus of the Understanding ATTR- CM discussion, hosted by BlackDoctor and sponsored by BridgeBio Pharma, Inc., which brought together cardiologists, medical experts, and a patient advocate to highlight the science, lived experience, and importance of early recognition and treatment.
Caused by unstable transthyretin (TTR) proteins that break apart and form amyloid deposits in the heart, ATTR-CM can lead to fatigue, shortness of breath, irregular heart rhythms, and eventually heart failure. Despite its severity, ATTR-CM remains widely underdiagnosed, in part because its symptoms often mimic other health issues or get dismissed as normal aging.