Pathophysiology

Introduction: Amyloidosis is a heterogeneous disease that results from the deposition of toxic insoluble beta-sheet fibrillar protein aggregates in different…

The amyloidoses are a group of systemic diseases characterized by organ deposition of misfolded protein fragments of diverse origins. The natural history of the…

Wild-type transthyretin cardiac amyloidosis (ATTRwt), formerly called senile cardiac amyloidosis (SCA), is almost exclusively a disorder of older adults. As the…

Amyloidosis is a term for diseases caused by extracellular deposition of protein fibrils. The accepted nomenclature is "AX", "A" for amyloidosis, and "X" indicating…