Diagnosed With ATTR-CM: What Should I Do Now?

Published: Nov 18, 2025
Category
Education
Key Information
Source
EveryDay Health
Year
2025
summary/abstract

Transthyretin cardiac amyloidosis (ATTR-CM)external link, opens in a new tab is a rare and incurable heart muscle disease. If you have ATTR-CM, proteins accumulate in your heart and hinder its ability to pump blood throughout your body, leading to a severe form of heart failure. Though treatments can help, this condition can also have a big effect on your quality of life.

What Does ATTR-CM Mean for Me?

ATTR-CM can be a life-changing diagnosis. Although its symptoms are not always strong at first, ATTR-CM is considered a progressive disease, one that generally gets worse over time, often leading to heart failure and atrial fibrillationexternal link, opens in a new tab. The hallmark symptomsexternal link, opens in a new tab include:

  • Shortness of breath
  • Bloated stomach
  • Confusion
  • Coughing or wheezing
  • Fatigue
  • Heart palpitations

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