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Familial Mediterranean Fever (Recurrent Polyserositis)

Published: Dec 14, 2016
Category
Reference Materials
Key Information
Source
Europe PMC
Year
2016
summary/abstract
Familial Mediterranean fever (FMF) is divided into two phenotypes: Type 1 and Type 2
* FMF type 1 is characterized by recurrent short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and, rarely, pericarditis and meningitis. The symptoms and severity vary among affected individuals, sometimes even among members of the same family. Amyloidosis, which can lead to renal failure, is the most severe complication, if untreated.
* FMF type 2 is characterized by amyloidosis as the first clinical manifestation of FMF in an otherwise asymptomatic individual.
Abstract Source
https://europepmc.org/books/NBK1227
Authors
Mordechai Shohat
Organisation
Sackler School of Medicine, Israel

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