Clinical Trials and Research

Amyloidosis is a rare disease involving the formation and spread of abnormal proteins in the body. Unlike with other proteins, the body cannot naturally recycle…

PurposeAmyloid positron emission tomography (PET) tracers are increasingly used to detect cardiac amyloidosis (CA). 11C-Pittsburgh compound B (PiB) and 1⁸F-…

CAMBRIDGE, Mass. - Alnylam Pharmaceuticals (NASDAQ:ALNY) announced Tuesday partnerships with Viz.ai and the American Heart Association aimed at improving early…

AL amyloidosis is when abnormal proteins called light chains collect in organs. UCSF is studying a drug for people with relapsed or refractory multiple myeloma or…

a study on AL AmyloidosisAmyloidosisOpen-label Phase 1b/2 study with primary objective of this study is to evaluate the safety, tolerability and efficacy of AZD0120…

Amyloidosis is a group of protein-folding disorders characterized by the infiltration of multiple organs with amyloid deposits, primarily affecting the heart and…

AbstractPurpose of ReviewCardiac amyloidosis (CA) results from myocardial infiltration by misfolded amyloidogenic proteins and represents a heterogeneous group of…

Jimmy Addison had just moved from Atlanta to Seneca, South Carolina, when he noticed something wasn’t right. “I started gaining weight and didn't know what was…

Cardiac amyloidosis can cause congestive heart failure, arrhythmias, and heart blocks, which frequently require cardiac device implantation (CDI). However, the…

Transthyretin amyloid cardiomyopathy (ATTR-CM) has been traditionally considered a rare and inexorably fatal condition. However, the development of therapies able…