Key Information
Source
The Johns Hopkins University
summary/abstract
Cardiac amyloidosis occurs when plaques of protein byproduct called amyloid build up in heart muscle, affecting its ability to pump blood. To confirm a diagnosis of cardiac amyloidosis, you will need either a cardiac biopsy or technetium pyrophosphate scan.
A cardiac biopsy involves taking a small sample of heart tissue that the doctor examines under the microscope. A technetium pyrophosphate scan is similar to an MRI in that it gives a picture of the heart. A dye is injected before the scan and will cause transthyretin amyloidosis to "light up." If either test indicates TTR amyloidosis, genetic testing is recommended to confirm the subtype.
Abstract Source
https://www.hopkinsmedicine.org/health/conditions-and-diseases/cardiac-amyloidosis