Patient Education

Draft systems map of the early diagnosis of cardiac amyloidosis.
Feb 16, 2026
Testing the utility of the first step of system evaluation theory in creating a system map of care for cardiac amyloidosis early detection: A case study
AbstractBackgroundHeart failure is a clinical syndrome resulting from numerous pathological conditions. One cause of heart failure, transthyretin cardiac…
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Conformations of SpCas9 residues that could form potential interactions with guide RNA or target DNA, based on SpCas9-sgRNA-target DNA complex structure
Feb 02, 2026
Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility
AbstractAmyloid transthyretin (ATTR) amyloidosis is a fatal disease caused by the accumulation of misfolded transthyretin proteins. Although knocking down the TTR…
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ashpublications
Jan 27, 2026
Clinical Features of Systemic Amyloidosis: A Scoping Review
Key PointsThis scoping review maps the earliest clinical signs of AL, ATTRwt, and ATTRv amyloidosis to improve early recognition and diagnosis.Distinct red flags…
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CRISPR-Cas3
Jan 21, 2026
https://www.oreateai.com/blog/understanding-hattr-a-deep-dive-into-hereditary-transthyretin-amyloidosis/23903414f6a0a602d9aca557d23f138c
Could CRISPR-Cas3 present itself as a potential therapeutic approach for genetic disorders like transthyretin amyloidosis (ATTR)?Researchers from the Institute of…
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transthyretin cardiac amyloidosis (ATTR-CM)
Jan 20, 2026
How to Manage Nerve Damage if You Have ATTR-CM
If you have transthyretin cardiac amyloidosis (ATTR-CM)external link, opens in a new tab, the same misshapen proteins that affect your heart can also build up…
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amyloidbiopsycarpal tunnelscreeningtenosynoviumtransthyretin
Jan 13, 2026
Early Diagnosis of ATTR-CM Using Carpal Tunnel Biopsy Examination: EDUCATE: A United Kingdom Prospective Multicenter Study
AbstractBackgroundTransthyretin amyloid cardiomyopathy (ATTR-CM) is an increasingly recognized but still underdiagnosed cause of heart failure in older people,…
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The patient underwent pacemaker implantation with left bundle branch pacing.
Jan 08, 2026
Systemic light chain cardiac amyloidosis with atrioventricular block
BackgroundSystemic light-chain (AL) amyloidosis is a rare plasma cell disorder with an annual incidence of approximately 8–12 cases per million population in…
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Electrocardiograms acquired on admission (A) and at two (B) and four (C) years thereafter. Panels A, B, and C show sinus rhythm and complete right bundle branch block. The R-wave amplitude in lead V5 progressively decreased, with values of 1.9 mV, 1.4 mV, and 1.0 mV for Panels A, B, and C, respectively.
Jan 05, 2026
Technetium-99m-labeled pyrophosphate uptake in the rectum of a patient with wild-type transthyretin cardiac amyloidosis
AbstractWild-type transthyretin amyloidosis is a disease characterized by deposition of transthyretin amyloid protein in systemic organs and tissues, especially the…
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For BNP, a normal level is less than 81 picograms per milliliter. For cTnI, a normal level is less than 0.1 nanograms per milliliter. Doctors stage amyloidosis based on these test results.
Jan 02, 2026
Stages of Amyloidosis: Breakdown by Type and More
If you’ve been diagnosed with amyloidosis, your doctor will assess how far the disease has progressed. This is called staging. As you go through amyloidosis…
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The median nerve runs through the carpal tunnel. When the median nerve is compressed, it can cause feelings of pain, tingling, or numbness throughout much of the hand.
Jan 02, 2026
ATTR-CM Amyloidosis and Carpal Tunnel Syndrome: What’s the Connection?
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a type of amyloidosis that affects the heart. It happens when a protein called transthyretin builds up in the…
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