How to Manage Nerve Damage if You Have ATTR-CM

Published: Jan 20, 2026
Category
Patient Education
Key Information
Source
Everyday Health
Year
2026
summary/abstract

If you have transthyretin cardiac amyloidosis (ATTR-CM)external link, opens in a new tab, the same misshapen proteins that affect your heart can also build up around the nerves, leading to nerve damage, or neuropathy. Symptoms are wide-ranging, from tingling toes to dizziness and incontinence.

This transthyretin amyloidosis with polyneuropathy, sometimes called ATTR-PN, is a relatively rare but serious condition. It occurs in hereditary cases of ATTR-CM, in which you inherit a specific gene, and in wild-type cases, which have no known cause.

 

Authors
Jessica Migala