Nodular Pulmonary Amyloidosis: A Complex Disease With Malignancy Association | oneAMYLOIDOSISvoice
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Nodular Pulmonary Amyloidosis: A Complex Disease With Malignancy Association

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source: BMJ Case Reports

year: 2017

authors: Core JM, Alsaad AA, Jiang L, Patel NM

summary/abstract:

Pulmonary amyloidosis is a rare disease that incorporates deposition of amyloid microfibril material in the lung parenchyma. The condition generally presents as an indolent subacute-to-chronic pulmonary disease and requires tissue biopsy to establish the diagnosis.

Nodular pulmonary amyloidosis, a subtype of pulmonary amyloidosis, is characterised by special radiographic and pathological features. While the disease can be associated with inflammatory conditions; its association with mucosal-associated lymphoid tissue (MALT lymphoma) is unusual and carries management challenges. Herein, we illustrate a case study of nodular pulmonary amyloidosis associated with underlying MALT lymphoma in a patient with known systemic lupus erythematosus. 

The aim of this article is to share the management experience of this complex condition with the medical community and to conduct an up-to-date literature review on nodular pulmonary amyloidosis.

organization: Mayo Clinic Hospital Jacksonville, USA; Mayo Clinic Florida, USA

DOI: 10.1136/bcr-2017-220428

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