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Scientific literature and patient education texts
Voorlichting Over Amyloidose
source: Amyloidosis Support Groups
year: 2022
summary/abstract:Alle normale eiwitten in ons lichaam zijn afbreekbaar en recyclebaar. Amyloïdose is een ziekte waarbij abnormale eiwitten (amyloïde) resistent zijn om afgebroken te worden. Als gevolg daarvan deponeren de amyloïde-eiwitten zich en hopen zich op in de weefsels van het lichaam. Als amyloïde opbouwt in nieren, hart, lever, maag-darmkanaal of zenuwen zorgt het ervoor dat die organen slecht functioneren.
Daarom zijn de symptomen van amyloïdose geassocieerd met abnormale werking van de betrokken organen. Doorgaans zullen patiënten een aantal van de volgende symptomen hebben: onverklaarbaar gewichtsverlies, vermoeidheid, kortademigheid, schuimende urine, zwelling in de enkels en benen alsmede gevoelloosheid en tintelen van de handen en voeten. Dit zijn manifestaties van schade aan onderliggende organen door het onoplosbare amyloïde-eiwit.
Behandelingen zijn erop gericht om ofwel de amyloïdeafzettingen te ontbinden of hun productie te onderbreken. Indien onbehandeld kan de ziekte levensbedreigend zijn. Daarom is vroege en nauwkeurige diagnose de sleutel tot het bevorderen van positieve resultaten.
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