Scientific Articles

ABSTRACTBackgroundIn the pivotal Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT), tafamidis significantly reduced mortality rates, leading to…

Awareness of transthyretin amyloid cardiomyopathy (ATTR-CM) has increased over the years due to diagnostic and therapeutic developments. Timely initiation of novel…

Simple SummaryLight-chain (AL) amyloidosis is a rare disease similar to the more common disease, multiple myeloma (MM). Both are caused by proliferation of…

A 76-year-old woman was found to have abnormally enlarged and calcified bilateral axillary lymph nodes on a screening mammogram (Figure 1). These correlated with…

Extract A 76-year-old woman was found to have abnormally enlarged and calcified bilateral axillary lymph nodes on a screening mammogram (Figure 1). These…

Cardiac amyloidosis used to be considered an ultra-rare disease with no treatment options. No longer. Advances in noninvasive testing have led to greater awareness…

IntroductionTransthyretin amyloidosis (ATTR) is a progressive, heterogeneous rare disease manifesting as ATTR polyneuropathy (ATTR-PN), ATTR cardiomyopathy (ATTR-CM…

AL amyloidosis is caused by the excessive production of nonfunctional immunoglobulins, leading to the formation of amyloid fibrils that damage vital organs,…