Scientific Articles
Nov 05, 2017
Emerging Therapeutic Targets Currently Under Investigation for the Treatment of Systemic Amyloidosis
Systemic amyloidosis occurs when one of a growing list of circulating proteins acquires an abnormal fold, aggregates and gives rise to extracellular amyloid…
Nov 03, 2017
Cardiac amyloidosis (CA) has been believed to be a rare disease for a long time, but recent sophisticated diagnostic modalities demonstrate that a considerable…
Oct 19, 2017
Objectives:
Immunoparesis (IP) is a risk factor associated with an unfavourable outcome in several plasma cell disorders. It has been suggested that its presence in…
Oct 14, 2017
Pulmonary amyloidosis is a rare disease that incorporates deposition of amyloid microfibril material in the lung parenchyma. The condition generally presents as an…
Oct 05, 2017
Very few prospective clinical trials have been conducted in advanced cardiac AL amyloidosis due to the rarity of the disease and challenging clinical course of the…
Sep 26, 2017
AL amyloidosis is a rare plasma cell dyscrasia characterized by multi-organ involvement and poor prognosis. We retrospectively evaluated the organ response (OR) and…
Sep 19, 2017
Amyloid tends to deposit in the gastrointestinal tract, which, being easily accessible, is often the target organ for a pathological diagnostic examination.…
Sep 10, 2017
Purpose:
Among patients with familial amyloidosis, mutation in the transthyretin (TTR) protein is the most common type. Patients with TTR amyloidosis have been…
Aug 15, 2017
Amyloidosis is a condition characterized by the extracellular deposition of amyloid, a fibrillary substance consisting of low-molecular-weight protein subunits.…
Jul 12, 2017
The amyloidoses are a group of systemic diseases characterized by organ deposition of misfolded protein fragments of diverse origins. The natural history of the…