Scientific Articles

Jan 09, 2018
New Concepts in the Treatment and Diagnosis of Amyloidosis
The most common form of systemic amyloidosis in Western countries is light chain amyloidosis. It is characterized by the deposition of a misfolded light chain in…
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Jan 04, 2018
Treatment Patterns and Health Care Resource Utilization Among Patients With Relapsed/Refractory Systemic Light Chain Amyloidosis
Background: Treatment for patients with systemic light chain (AL) amyloidosis remains challenging. Our study aims to describe treatment patterns for both newly…
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Dec 31, 2017
Case Report: Treatment of Light-Chain Amyloidosis With Daratumumab Monotherapy in Two Patients
Immunoglobulin light-chain amyloidosis (AL) affects multiple organs, most prominently the kidney and the heart. Renal and cardiac impairment are both associated…
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Dec 19, 2017
Right Ventricular Longitudinal Strain: A Tool for Diagnosis and Prognosis in Light-Chain Amyloidosis
Objectives: Light-chain (AL) amyloidosis can lead to an infiltrative cardiomyopathy with increased wall thickness (IWT) of very poor prognosis. Our primary aim was…
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Dec 13, 2017
Gastrointestinal Perforation in Light Chain Amyloidosis in the Era of Novel Agent Therapy: A Case Series and Review of the Literature
Gastrointestinal (GI) perforation is remarkably rare in patients with light chain (AL) amyloidosis and has not yet been reported in patients with AL amyloidosis…
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Nov 05, 2017
Emerging Therapeutic Targets Currently Under Investigation for the Treatment of Systemic Amyloidosis
Systemic amyloidosis occurs when one of a growing list of circulating proteins acquires an abnormal fold, aggregates and gives rise to extracellular amyloid…
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