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In collaboration with F Hoffmann-la Roche & Co Ltd we have developed a new chemical entity, carboxy pyrrolidone hexanoyl pyrrolidone carboxylic acid (CPHPC),…

Since starting HeartValveSurgery.com nearly twenty years ago, I have learned a lot about the heart. However, it was not until I received this email from David…

Key takeaways:ALXN2220, a novel investigational depleter monoclonal antibody, was granted fast track designation by the FDA.It is designed for the treatment of…

BackgroundImmunoglobulin light-chain amyloidosis is a relatively rare condition with a worldwide incidence of 5.1–12.8 cases per million person-years (Baker, 2022…

A 71-year-old healthy White male presented in 2010 with intermittent redness in the right eye nasally for 10 years. On examination, corrected visual acuity was 20/…

The FDA has granted 510(k) clearance to a Centiloid scaling apparatus software for positron emission tomography-based amyloid imaging to evaluate individuals for…

Amyloidosis is a localized or systemic disease caused by deposition of proteins in the extracellular space of various organs and tissues. As part of the disease,…

Amyloid fibrils, crystal-like fibrillar aggregates of denatured proteins, are formed linked with the breakdown of supersaturation, causing a series of amyloidosis…

PET/CT imaging with iodine-124 (I-124) evuzamitide may help monitor how patients with cardiac amyloidosis respond to therapy over time, according to a study…

Caring for complex clients can be both rewarding and challenging. This highlights the importance of a strong support network for providing the best possible…