Education
Jan 04, 2018
Background:
Treatment for patients with systemic light chain (AL) amyloidosis remains challenging. Our study aims to describe treatment patterns for both newly…
Jan 03, 2018
The term informed consent is mistakenly viewed as the same as getting a research participant's signature on the consent form. FDA believes that obtaining a…
Dec 31, 2017
Immunoglobulin light-chain amyloidosis (AL) affects multiple organs, most prominently the kidney and the heart. Renal and cardiac impairment are both associated…
Dec 21, 2017
Introduction:
Amyloidosis is a heterogeneous disease that results from the deposition of toxic insoluble beta-sheet fibrillar protein aggregates in different…
Dec 19, 2017
Right Ventricular Longitudinal Strain: A Tool for Diagnosis and Prognosis in Light-Chain Amyloidosis
Objectives:
Light-chain (AL) amyloidosis can lead to an infiltrative cardiomyopathy with increased wall thickness (IWT) of very poor prognosis. Our primary aim was…
Dec 13, 2017
Gastrointestinal (GI) perforation is remarkably rare in patients with light chain (AL) amyloidosis and has not yet been reported in patients with AL amyloidosis…
Nov 05, 2017
Emerging Therapeutic Targets Currently Under Investigation for the Treatment of Systemic Amyloidosis
Systemic amyloidosis occurs when one of a growing list of circulating proteins acquires an abnormal fold, aggregates and gives rise to extracellular amyloid…
Nov 03, 2017
Cardiac amyloidosis (CA) has been believed to be a rare disease for a long time, but recent sophisticated diagnostic modalities demonstrate that a considerable…
Oct 19, 2017
Objectives:
Immunoparesis (IP) is a risk factor associated with an unfavourable outcome in several plasma cell disorders. It has been suggested that its presence in…