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Deep inside the liver, billions of protein molecules are produced every day. Sometimes, due to aging or genetic factors a particular protein, transthyretin (also…

Webinar Session: Wednesday, February 11th at 6 PM (ET) Zoom Meeting(These sessions will not be recorded due to patient involvement and HIPAA laws)To Register …

AbstractBackgroundMost intracerebral hemorrhages (ICH) are caused by 1 of 2 cerebral small vessel diseases (cSVDs): arteriolosclerosis and cerebral amyloid…

Carol Boyers' carpal tunnel history raised some red flags for her doctor. After three surgeries on her right hand, he suggested a biopsy.“Just a small little…

The introduction of anti-amyloid monoclonal antibody therapies for Alzheimer’s disease highlights the growing importance of ARIA (Amyloid-Related Imaging…

Study OverviewBrief SummaryThe TRACE-AI Diagnostic Study will evaluate the performance of artificial intelligence (AI) models applied to electrocardiograms (AI-ECG…

INTRODUCTION. This issue focuses on amyloid heart disease and related diagnostic and therapeutic challenges. The articles explore topics such as disease burden,…

https://doi.org/10.1016/j.jacc.2025.10.019Get rights and contentRefers toEffect of Acoramidis on Recurrent and Cumulative Cardiovascular Outcomes in ATTR-CMJACC,…

AbstractBackgroundImmunoglobulin light chain (AL) amyloidosis is a well-recognized complication of multiple myeloma (MM), with important prognostic implications.…

AbstractOur perspective addresses one of the most pressing and timely debates in contemporary neurology and health policy: whether the recent approval of anti-…