Patient Education

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Jan 27, 2026

Clinical Features of Systemic Amyloidosis: A Scoping Review

Key PointsThis scoping review maps the earliest clinical signs of AL, ATTRwt, and ATTRv amyloidosis to improve early recognition and diagnosis.Distinct red flags…

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CRISPR-Cas3

Jan 21, 2026

https://www.oreateai.com/blog/understanding-hattr-a-deep-dive-into-hereditary-transthyretin-amyloidosis/23903414f6a0a602d9aca557d23f138c

Could CRISPR-Cas3 present itself as a potential therapeutic approach for genetic disorders like transthyretin amyloidosis (ATTR)?Researchers from the Institute of…

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transthyretin cardiac amyloidosis (ATTR-CM)

Jan 20, 2026

How to Manage Nerve Damage if You Have ATTR-CM

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Draft systems map of the early diagnosis of cardiac amyloidosis.

Jan 16, 2026

Testing the utility of the first step of system evaluation theory in creating a system map of care for cardiac amyloidosis early detection: A case study

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amyloidbiopsycarpal tunnelscreeningtenosynoviumtransthyretin

Jan 13, 2026

Early Diagnosis of ATTR-CM Using Carpal Tunnel Biopsy Examination: EDUCATE: A United Kingdom Prospective Multicenter Study

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The patient underwent pacemaker implantation with left bundle branch pacing.

Jan 08, 2026

Systemic light chain cardiac amyloidosis with atrioventricular block

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Electrocardiograms acquired on admission (A) and at two (B) and four (C) years thereafter. Panels A, B, and C show sinus rhythm and complete right bundle branch block. The R-wave amplitude in lead V5 progressively decreased, with values of 1.9 mV, 1.4 mV, and 1.0 mV for Panels A, B, and C, respectively.

Jan 05, 2026

Technetium-99m-labeled pyrophosphate uptake in the rectum of a patient with wild-type transthyretin cardiac amyloidosis

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Conformations of SpCas9 residues that could form potential interactions with guide RNA or target DNA, based on SpCas9-sgRNA-target DNA complex structure

Jan 02, 2026

Targeting transthyretin by one Cas9 variant with superfidelity and broad compatibility

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Jan 02, 2026

Stages of Amyloidosis: Breakdown by Type and More

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The median nerve runs through the carpal tunnel. When the median nerve is compressed, it can cause feelings of pain, tingling, or numbness throughout much of the hand.

Jan 02, 2026

ATTR-CM Amyloidosis and Carpal Tunnel Syndrome: What’s the Connection?

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Newsletter

RNAi Explained

Dr. Bersell explores RNA interference (RNAi) technology and its applications in treating ATTR-CM and ATTR-PN. Learn about mechanism of action, clinical evidence, and patient outcomes.

Expert Perspectives on Attruby®

Dr. Barry Trachtenberg and ATTR community members discuss Attruby™ (acoramidis), covering clinical data, patient perspectives, and treatment considerations.

Watch Discussion

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