News

AbstractAmyloidosis associated with mutations in the transthyretin gene is the most common form of hereditary systemic amyloidosis. The onset and phenotype of the…

I-evuzamitide positron emission tomography/computed tomography (PET/CT) can help diagnose heart involvement in rare forms of amyloidosis as well as transthyretin-…

The U.S. Food and Drug Administration (FDA) has granted fast track designation to coramitug, an experimental treatment in late-stage clinical testing for…

Key TakeawaysATTR-CM results from TTR accumulation causing ventricular thickening and diastolic dysfunction, presenting with dyspnea, edema, congestion, tachycardia…

ATTR-CM is the zebra hiding among the horses. AI may finally be the tool that finds it. Experts Drs Kevin Alexander and Lily Stern explore what's working, what's…

The FDA granted Fast Track Designation to coramitug, an investigational anti-TTR antibody designed to clear existing amyloid deposits in ATTR cardiomyopathy.The US…

AboutThe purpose of this study is to investigate the effect of eplontersen compared to placebo on the reduction of serum TTR concentration and long-term safety in…

Transthyretin (ATTR) amyloidosis is a progressive fatal disease caused by the deposition of transthyretin derived amyloid fibrils in various organs [1]. The disease…

DUBLIN - The U.S. Food and Drug Administration has granted Fast Track Designation to coramitug, an investigational antibody for treating ATTR amyloidosis with…

Patients enrolled in more recent clinical trials for transthyretin-mediated amyloid cardiomyopathy (ATTR-CM) exhibited baseline characteristics consistent with less…